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In response, NAD+ turns on particular enzymes that might promote healthy aging. Nicotinamide riboside supplements changes body make-up and skeletal muscle acetylcarnitine concentrations in healthy overweight humans. Seldeen KL, Shahini A, Thiyagarajan R, et al.

Airhart SE, Shireman LM, Risler LJ, et al. An open-label, non-randomized research study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its results on blood NAD+ degrees in healthy volunteers. Like other types of vitamin B3, nicotinamide riboside is transformed by your body right into nicotinamide adenine dinucleotide (NAD+), a coenzyme or helper molecule.